Hydroxyurea and Cataracts
I'm reading with interest that Betty Schulman's cataracts were caused by hydroxyurea. I am also using hydroxyurea to control platelets, and I was told last week by my eye doctor that I am developing cataracts. My question to you is if backing off the medicine would stop the cataract problem. How much of the hydroxyurea did Betty take in mgs per day and did she stop taking the medicine altogether or just reduce the amount? I would appreciate very much if you would give me an answer. Thank you
Most packaged and commercial doses of hydroxyurea is about 500 mg taken at once a day, although the actual usages is about 30-80 mg a day. Hydroxyurea is used to treat tumors, although the problems of such use causes cataract, the conditions of cataract usually disappears or lessens within a weeks. It is often described as a reversible cataract condition. While I do use some hydroxyurea, I don't use to treat cancer but it is used as an antioxidants and to help sleep although the dose I used is a lot less than anyone, which is only 1-2 mg per day. Hydroxyurea is actually a natural by-product in the body where hydroxylamine hydrochloride is reacted with with bicarbonates to form hydroxyurea. There are some indirect evidence from the use of hydroxylamine hydrochloride to reduce glycation and hence some of my occasional use as an antioxidant, being that it's Oxidation Reduction Potential is negative when millivolts when the solution is alkaline, as well as this having antiviral properties and hence it's use as an anti-tumor agent. If the amount is reduced so that it won't cause cataract, the only dose I know that doesn't have that effect is the dose I have used for other purposes which is between 1-5 mg. I think the dose of 250-500 mg is far to high and causes drowsiness and it's the high dose is what causing the cataract.
The other dose that may lessen cataract that are used is also between 30-80, but for some reason commercially they use 500 mg. So if some reduction of cataract, my guess is 30-80 mg, but the dose that does not cause cataract is quite small at 1-5 mg. In my opinion much of the anti-cancer effects of hydroxyurea is it's ability to kill cancer virus, but if this is so there are many other things that are also antiviral that can be used together so the dose can be lowered such as olive leaf extract, zinc gluconate, EDTA, magnesium gluconate, pomegranate fruits, apricots pits. When they are combined each of the dose are all reduced to a safer level where it won't effect the cataract. Taking some L-carnosine and chinese wolfberries, especially the L-carnosine I have known it to help reverse the cataract too.
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